About This Drug
Exemestane is used to treat cancer. It is given orally (by mouth).
Possible Side Effects
- Hot flashes or sudden skin flushing may happen. You may also feel warm or red.
- Trouble sleeping
- Pain in the joints
- Increased sweating
Note: Each of the side effects above was reported in 10% or greater of patients treated with exemestane. Not all possible side effects are included above.
Warnings and Precautions
Decrease in your bone mass, which may put you at risk of bone fractures
How to Take Your Medication
- Swallow the medicine whole after a meal.
- Handling: Wash your hands after handling your medicine, your caretakers should not handle your medicine with bare hands and should wear latex gloves.
- Storage: Store this medicine in the original container at room temperature. Discuss with your nurse or your doctor how to dispose of unused medicine.
Treating Side Effects
Drink plenty of fluids (a minimum of eight glasses per day is recommended).
If you throw up or have loose bowel movements, you should drink more fluids so that you do not become dehydrated (lack water in the body from losing too much fluid).
To help with nausea and vomiting, eat small, frequent meals instead of three large meals a day. Choose foods and drinks that are at room temperature. Ask your nurse or doctor about other helpful tips and medicine that is available to help or stop lessen these symptoms.
Manage tiredness by pacing your activities for the day. Be sure to include periods of rest between energy-draining activities.
Keeping your pain under control is important to your well-being. Please tell your doctor or nurse if you are experiencing pain.
If you are having trouble sleeping, talk to your nurse or doctor on tips to help you sleep better.
Food and Drug Interactions
There are no known interactions of exemestane with food, however this medication should be taken with food.
Check with your doctor or pharmacist about all other prescription medicines and dietary supplements you are taking before starting this medicine as there are known drug interactions with exemestane. Also, check with your doctor or pharmacist before starting any new prescription or over-the-counter medicines, or dietary supplement to make sure that there are no interactions.
Avoid the use of St. John’s Wort while taking exemestane as this may lower the levels of the drug in your body, which can make it less effective.
Avoid the use of estrogen containing products while taking exemestane as this may lower the levels of the drug in your body, which can make it less effective.
When to Call the Doctor
Call your doctor or nurse if you have any of these symptoms and/or any new or unusual symptoms:
- Nausea that stops you from eating or drinking and/or is not relieved by prescribed medicines
- Throwing up more than 3 times a day
- Fatigue that interferes with your daily activities
- Pain that does not go away, or is not relieved by prescribed medicines
- A headache that does not go away
- If you think you may be pregnant
- Pregnancy warning: This drug may have harmful effects on the unborn baby. Women of child bearing potential should use effective methods of birth control during your cancer treatment and for at least 1 month after treatment. Let your doctor know right away if you think you may be pregnant.
- Breastfeeding warning: Women should not breast feed during treatment and for 1 month after treatment because this drug could enter the breast milk and cause harm to a breast feeding baby.
- Fertility warning: In women and men, this drug may affect your ability to have children in the future. Talk with your doctor or nurse if you plan to have children. Ask for information on egg and sperm banking.