About This Drug
Nilutamide is used to treat cancer. It is given orally (by mouth).
Possible Side Effects
- Hot flashes or sudden skin flushing may happen. You may also feel warm or red.
- You may have difficulty seeing when going from a lighted area to a dark area.
Note: Each of the side effects above was reported in 10% or greater of patients treated with nilutamide. Not all possible side effects are included above.
Warnings and Precautions
- Inflammation (swelling) of the lungs. You may have a dry cough or trouble breathing.
- Changes in your liver function, which can be life-threatening
- This drug may impair your ability to drive, especially at night or through tunnels. Use caution and tell your nurse or doctor if you experience this effect.
- Nilutamide may cause intolerance to alcohol. Alcohol should be avoided if you experience hot flashes, skin flushing, general discomfort or have a feeling of being unwell after drinking alcohol.
How to Take Your Medication
- Swallow the medicine whole with or without food.
- Missed dose: If you vomit or miss a dose, take your next dose at the regular time, and contact your physician. Do not take 2 doses at the same time and do not double up on the next dose
- Handling: Wash your hands after handling your medicine, your caretakers should not handle your medicine with bare hands and should wear latex gloves.
- Storage: Store this medicine in the original container at room temperature. Discuss with your nurse or your doctor how to dispose of unused medicine
Food and Drug Interactions
- There are no known interactions of nilutamide with food.
- Check with your doctor or pharmacist about all other prescription medicines and over-the-counter medicines and dietary supplements (vitamins, minerals, herbs and others) you are taking before starting this medicine as there are known drug interactions with nilutamide. Also, check with your doctor or pharmacist before starting any new prescription or over-the-counter medicines, or dietary supplements to make sure that there are no interactions.
- There are known interactions of nilutamide with blood thinning medicine such as warfarin. Ask your doctor what precautions you should take.
When to Call the Doctor
Call your doctor or nurse if you have any of these symptoms and/or any new or unusual symptoms:
- Fever of 100.5 F (38 C) or higher
- Pain in your chest
- Dry cough
- Trouble breathing
- Signs of possible liver problems: dark urine, pale bowel movements, bad stomach pain, feeling very tired and weak, unusual itching, or yellowing of the eyes or skin
- If you think you may be pregnant
- Pregnancy warning: It is not known if this drug may harm an unborn child.For this reason, be sure to talk with your doctor if you are pregnant or planning to become pregnant while receiving this drug. Let your doctor know right away if you think you may be pregnant (or may have impregnated your partner.)
- Breastfeeding warning: It is not known if this drug passes into breast milk. For this reason, women should talk to their doctor about the risks and benefits of breastfeeding during treatment with this drug because this drug may enter the breast milk and cause harm to a breastfeeding baby.
- Fertility warning: Human fertility studies have not been done with this drug. Talk with your doctor or nurse if you plan to have children.Ask for information on sperm or egg banking.
Revised March 2018
This information is intended to provide helpful health information to the general public and is not to be used in place of any medical, health, psychological, or any other kind of personal professional services. The information herein does not cover all possible uses, actions, precautions, side effects, or interactions of the medicines mentioned, nor is the information intended as medical advice for individual problems or for making an evaluation as to the risks and benefits of taking a particular medication. The dose, method of administration and contraindications for any administered medication should be confirmed before use. UPMC specifically disclaims all responsibility for any liability, loss or risk, personal or otherwise, which is incurred as a consequence, directly or indirectly, of the use and application of any medication mentioned herein.