Other Names: Nplate®
About This Drug
Romiplostim is used to treat chronic immune thrombocytopenia (ITP). It is given as an injection under the skin (subcutaneously).
Possible Side Effects
- Muscle, and joint pain
- Feeling dizzy
- Trouble sleeping
- Pain in arms and/or legs
- Pain in the abdomen
- Shoulder pain
- Numbness, tingling in your hands and feet
Note: Each of the side effects above was reported in 5% or greater of patients treated with romiplostim. Not all possible side effects are included above.
Warnings and Precautions
- This drug may increase your risk of getting leukemia if you already have a condition called myelodysplastic syndrome.
- Blood clots. A blood clot in your leg may cause your leg to swell, appear red and warm, and/or cause pain. A blood clot in your lungs may cause trouble breathing, pain when breathing, and/or chest pain.
- This drug may not work or may stop working. If this happens, your doctor may check your blood for antibodies to this drug.
Treating Side Effects
- If you are dizzy, get up slowly after sitting or lying.
- If you have numbness and tingling in your hands and feet, be careful when cooking, walking, and handling sharp objects and hot liquids.
- Keeping your pain under control is important to your well-being. Please tell your doctor or nurse if you are experiencing pain.
- If you are having trouble sleeping, talk to your nurse or doctor on tips to help you sleep better.
Food and Drug Interactions
- There are no known interactions of romiplostim with food.
- This drug may interact with other medicines. Tell your doctor and pharmacist about all the medicines and dietary supplements (vitamins, minerals, herbs and others) that you are taking at this time. The safety and use of dietary supplements and alternative diets are often not known. Using these might affect your cancer or interfere with your treatment. Until more is known, you should not use dietary supplements or alternative diets without your cancer doctor's help.
When to Call the Doctor
Call your doctor or nurse if you have any of these symptoms and/or any new or unusual symptoms:
- Your leg or arm is swollen, red, warm and/or painful
- Wheezing and/or trouble breathing
- Pain in your chest
- Numbness, tingling, or pain your hands and feet
- Feeling dizzy or lightheaded
- Fatigue that interferes with your daily activities
- Pain that does not go away, or is not relieved by prescribed medicines
- Easy bleeding or bruising
- If you think you are pregnant
- Pregnancy warning: It is not known if this drug may harm an unborn child. For this reason, be sure to talk with your doctor if you are pregnant or planning to become pregnant while getting this drug. Let your doctor know right away if you think you may be pregnant.
- Breast feeding warning: It is not known if this drug passes into breast milk. For this reason, women should talk to their doctor about the risks and benefits of breast feeding during treatment with this drug because this drug may enter the breast milk and cause harm to a breast feeding baby.