Triptoerlin

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About This Drug

Triptorelin is used to treat cancer. It is given as an injection in your muscle (intramuscularly).

Possible Side Effects

  • Hot flashes or sudden skin flushing may happen. You may also feel warm or red.
  • Headache
  • Bone pain
  • Impotence (erectile dysfunction)
  • Shrinking of your testicles
  • Swelling of your legs, ankles and/or feet
  • Leg pain

Note:Each of the side effects above was reported in 5% or greater of patients treated with triptorelin. Not all possible side effects are included above.

Warnings and Precautions

  • Allergic reactions, including anaphylaxis are rare but may happen in some patients. Signs of allergic reaction to this drug may be swelling of the face, feeling like your tongue or throat are swelling, trouble breathing, rash, itching, fever, chills, feeling dizzy, and/or feeling that your heart is beating in a fast or not normal way. If this happens, do not take another dose of this drug. You should get urgent medical treatment.
  • Tumor flare phenomenon. During the first few weeks, typical signs and symptoms of your cancer may worsen. You also may have an increase in bone pain. In men, obstruction of urine flow and compression of spinal cord can happen very rarely. Let your doctor know if you have any difficulties in urinating, moving your bowels, or numbness, tingling, or pain in your legs and feet.
  • Changes in your heart function, abnormal heart beat and/or risk of heart attack
  • Blood sugar levels may change. If you have diabetes, changes may need to be made to your diabetes medication.
  • Stroke. Symptoms of a stroke such as sudden numbness or weakness of your face, arm, or leg, especially on one side of your body; sudden confusion, trouble speaking or understanding; sudden trouble seeing in one or both eyes; sudden trouble walking, feeling dizzy, loss of balance or coordination; or sudden bad headache with no known cause.If you have any of these symptoms for 2 minutes, call 911.

Note: Some of the side effects above are very rare. If you have concerns and/or questions, please discuss them with your medical team.

Treating Side Effects

  • Keeping your pain under control is important to your well-being. Please tell your doctor or nurse if you are experiencing pain.
  • If you have diabetes, keep good control of your blood sugar level. Tell your nurse or your doctor if your glucose levels are higher or lower than normal.

Food and Drug Interactions

  • There are no known interactions of triptorelin with food and other medications.
  • Tell your doctor and pharmacist about all the medicines and dietary supplements (vitamins, minerals, herbs and others) that you are taking at this time. The safety and use of dietary supplements and alternative diets are often not known. Using these might affect your cancer or interfere with your treatment. Until more is known, you should not use dietary supplements or alternative diets without your cancer doctor's help.

When to Call the Doctor

Call your doctor or nurse if you have any of these symptoms and/or any new or unusual symptoms:

  • Headache that does not go away
  • Symptoms of a stroke such as sudden numbness or weakness of your face, arm, or leg, especially on one side of your body; sudden confusion, trouble speaking or understanding; sudden trouble seeing in one or both eyes; sudden trouble walking, feeling dizzy, loss of balance or coordination; or sudden bad
  • Feeling that your heart is beating in a fast or not normal way (palpitations)
  • Feeling dizzy or lightheaded
  • Chest pain or symptoms of a heart attack. Most heart attacks involve pain in the center of the chest that lasts more than a few minutes. The pain may go away and come back or it can be constant. It can feel like pressure, squeezing, fullness, or pain. Sometimes pain is felt in one or both arms, the back, neck, jaw, or stomach. If any of these symptoms last 2 minutes, call 911.
  • Signs of allergic reaction: swelling of the face, feeling like your tongue or throat are swelling, trouble breathing, rash, itching, fever, chills, feeling dizzy, and/or feeling that your heart is beating in a fast or not normal way
  • Abnormal blood sugar
  • Unusual thirst, passing urine often, headache, sweating, shakiness, irritability
  • Pain that does not go away, or is not relieved by prescribed medicines
  • Weight gain of 5 pounds in one week (fluid retention)

Reproduction Warnings

  • Pregnancy warning: This drug may have harmful effects on the unborn baby. Triptorelin should never be used by women who are pregnant or who could become pregnant while taking the drug.
  • Breastfeeding warning: This drug is not for use in women. It is not known if this drug passes into breast milk. For this reason, women should talk to their doctor about the risks and benefits of breast feeding during treatment with this drug because this drug may enter the breast milk and cause harm to a breast feeding baby.
  • Fertility warning: Human fertility studies have not been done with this drug. Talk with your doctor or nurse if you plan to have children. Ask for information on sperm banking.

Revised January 2018

This information is intended to provide helpful health information to the general public and is not to be used in place of any medical, health, psychological, or any other kind of personal professional services. The information herein does not cover all possible uses, actions, precautions, side effects, or interactions of the medicines mentioned, nor is the information intended as medical advice for individual problems or for making an evaluation as to the risks and benefits of taking a particular medication. The dose, method of administration and contraindications for any administered medication should be confirmed before use. UPMC specifically disclaims all responsibility for any liability, loss or risk, personal or otherwise, which is incurred as a consequence, directly or indirectly, of the use and application of any medication mentioned herein.