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What Is Stereotactic Radiosurgery (SRS)?

Stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) are precise and effective types of radiation treatments for cancer.

They use concentrated radiation beams in high doses to destroy tumors in hard-to-reach areas of the body.

SRS treatments target tumors of the spine and the head and neck, including the brain. SBRT treatments target tumors in other parts of the body that may be hard to reach.

Stereotactic Radiosurgery Benefits

Both SRS and SBRT:

  • Are noninvasive treatments.
  • Require no anesthesia or incisions.
  • Minimize radiation damage to surrounding healthy tissue and organs.

Compared to other cancer treatments, other benefits include:

  • Fewer treatments. Most people don't need more than five SRS treatment sessions.
  • Less risk. Because SRS is noninvasive, most people have fewer complications and side effects.
  • Greater access to more tumors. SRS technology gives us the ability to treat cancers anywhere in the body, including hard-to-treat tumors.

Types of Radiosurgery Machines and Tumors We Treat

For 25 years, UPMC Hillman Cancer Center has been a leader in SRS.

SRS machines

We use these machines for stereotactic radiosurgery:

Cancers and benign tumors we treat using SRS machines

Using these machines, we treat the following cancers and other benign tumors:

Your doctor, with your input, will decide on a treatment plan. Your type of treatment will depend on your age and the type and stage of your cancer.

Contact UPMC CancerCenter About Stereotactic Radiosurgery


To learn more about SRS or refer a patient, call 855-777-3228 or email

Stereotactic Radiosurgery Program of UPMC CancerCenter
Mary Hillman Jennings Radiation Oncology Center
UPMC Shadyside
5230 Centre Ave.
Pittsburgh, PA 15232

Gamma Knife

To learn more about Gamma Knife for brain tumors or refer a patient,
call 1-877-986-9862.

UPMC Department of Neurosurgery
UPMC Presbyterian
Suite B-400
200 Lothrop Street
Pittsburgh, PA 15213