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Dutasteride (Avodart®)

About This Drug

Dutasteride is used to treat benign enlargement of the prostate. It is given orally (by mouth).

Possible Side Effects

  • Impotence (erectile dysfunction)
  • Decreased sex drive
  • Ejaculation disorders
  • Swelling of your breasts and/or breast pain

Note: Each of the side effects above was reported in 1% or greater of patients treated with dutasteride. Not all possible side effects are included above.

Warnings and Precautions

  • This drug may raise your risk of getting high-grade prostate cancer

Important Information

  • Do not donate blood during treatment and for at least 6 months after treatment.
  • This drug may affect prostate-specific antigen (PSA) levels used to detect prostate cancer.
  • Women who are pregnant or could become pregnant should not handle this medicine or touch any open or broken capsules because this drug can cause harm to unborn male baby. If any of the content of a broken capsules get on their skin, they should wash their hands with soap and water right away.

How to Take Your Medication

  • Swallow the medicine whole with or without food. Do not chew or open capsules.
  • Missed dose: If you miss a dose, take it as soon as you think about it on the same day. If not, continue with your regular dosing the next day; do not double up on the next dose.
  • If you vomit a dose, take your next dose at the regular time, and contact your physician. Do not take 2 doses at the same time and do not double up on the next dose.
  • Handling: Wash your hands after handling your medicine, your caretakers should not handle your medicine with bare hands and should wear latex gloves.
  • If any of the capsules are broken, leaking, discolored or deformed, do not touch them with bare hands. Carefully throw away the capsules and wash your hands after handling.
  • Storage: Store this medicine in the original container at room temperature. Avoid storing at high temperature since this may cause the capsules to become discolored and/or deformed.
  • Disposal of unused medicine: Do not flush any expired and/or unused medicine down the toilet or drain unless you are specifically instructed to do so on the medication label. Some facilities have take-back programs and/or other options. If you do not have a take-back program in your area, then please discuss with your nurse or your doctor how to dispose of unused medicine.

Food and Drug Interactions

  • This drug may interact with grapefruit and grapefruit juice. Talk to your doctor as this could make side effects worse.
  • This drug may interact with other medicines. Tell your doctor and pharmacist about all the prescription and over the counter medicines and dietary supplements (vitamins, minerals, herbs and others) that you are taking at this time. Also, check with your doctor or pharmacist before starting any new prescription or over-the-counter medicines, or dietary supplements to make sure that there are no interactions.

When to Call the Doctor

Call your doctor or nurse if you have any of these symptoms and/or any new or unusual symptoms:

  • Lumps in your breasts or nipple discharge

Reproduction Warnings

  • Pregnancy warning: This drug can have harmful effects on the unborn baby. Dutasteride is not indicated for use in women.
  • Breastfeeding warning: It is not known if this drug passes into breast milk. Dutasteride is not indicated for use in women.
  • Fertility warning: In men, this drug may affect your ability to have children in the future. Talk with your doctor or nurse if you plan to have children. Ask for information on sperm banking.

Revised June 2019

This patient information was developed by Via Oncology, LLC © 2019. This information is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have.

CLIENT acknowledges that the Via Pathways and Via Portal are information management tools only, and that Via Oncology, LLC has not represented the Via Pathways or Via Portal as having the ability to diagnose disease, prescribe treatment, or perform any other tasks that constitute the practice of medicine. The clinical information contained in the Via Pathways and Via Portal are intended as a supplement to, and not a substitute for, the knowledge, expertise, skill, and judgment of physicians, pharmacists and other healthcare professionals involved with patient care at CLIENT facilities.