Octreotide LAR Depot (Sandostatin® LAR Depot)
About This Drug
Octreotide LAR Depot is used to treat diarrhea or diarrhea associated with some types of cancer. It is given as an injection in your muscle (intramuscularly).
Possible Side Effects
- Pain in your abdomen
- Feeling dizzy
- Back pain
Note: Each of the side effects above was reported in 20% or greater of patients treated with octreotide LAR Depot. Not all possible side effects are included above.
Warnings and Precautions
- Inflammation of the gallbladder/gallstones. Possible signs are nausea/vomiting, fever, tenderness in the right side of the abdomen.
- Blood sugar levels may change.
- Changes in your thyroid function.
- Changes in your heart function such as abnormal heartbeat and EKG.
Note: Some of the side effects above are very rare. If you have concerns and/or questions, please discuss them with your medical team.
Treating Side Effects
- Manage tiredness by pacing your activities for the day.
- Be sure to include periods of rest between energy-draining activities.
- If you are dizzy, get up slowly after sitting or lying.
- Keeping your pain under control is important to your well-being. Please tell your doctor or nurse if you are experiencing pain.
- Drink plenty of fluids (a minimum of eight glasses per day is recommended).
- To help with nausea and vomiting, eat small, frequent meals instead of three large meals a day. Choose foods and drinks that are at room temperature. Ask your nurse or doctor about other helpful tips and medicine that is available to help stop or lessen these symptoms.
- If you have diabetes, keep good control of your blood sugar level. Tell your nurse or your doctor if your glucose levels are higher or lower than normal.
Food and Drug Interactions
- There are no known interactions of octreotide acetate with food.
- This drug may interact with other medicines. Tell your doctor and pharmacist about all the prescription and over-the-counter medicines and dietary supplements (vitamins, minerals, herbs and others) that you are taking at this time. Also, check with your doctor or pharmacist before starting any new prescription or over-the-counter medicines, or dietary supplements to make sure that there are no interactions.
When to Call the Doctor
Call your doctor or nurse if you have any of these symptoms and/or any new or unusual symptoms:
- Fever of 100.4° F (38° C) or higher
- Headache that does not go away
- Feeling dizzy or lightheaded
- Tiredness that interferes with your daily activities
- Unexplained weight gain
- Feeling that your heart is beating in a fast or not normal way (palpitations)
- Trouble breathing
- Nausea that stops you from eating or drinking and/or is not relieved by prescribed medicines
- Pain in the right side of your abdomen
- Abnormal blood sugar
- Unusual thirst, passing urine often, headache, sweating, shakiness, irritability
- If you think you may be pregnant
- Pregnancy warning: It is not known if this drug may harm an unborn child. For this reason, be sure to talk with your doctor if you are pregnant or planning to become pregnant while receiving this drug. Let your doctor know right away if you think you may be pregnant. treatment with this drug because this drug may enter the breast milk and cause harm to a breastfeeding baby.
- Breastfeeding warning: It is not known if this drug passes into breast milk. For this reason, women should talk to their doctor about the risks and benefits of breastfeeding during treatment with this drug because this drug may enter the breast milk and cause harm to a breastfeeding baby.
- Fertility warning: Human fertility studies have not been done with this drug. Talk with your doctor or nurse if you plan to have children. Ask for information on sperm or egg banking.
Revised August 2019
This patient information was developed by Via Oncology, LLC © 2019. This information is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have.
CLIENT acknowledges that the Via Pathways and Via Portal are information management tools only, and that Via Oncology, LLC has not represented the Via Pathways or Via Portal as having the ability to diagnose disease, prescribe treatment, or perform any other tasks that constitute the practice of medicine. The clinical information contained in the Via Pathways and Via Portal are intended as a supplement to, and not a substitute for, the knowledge, expertise, skill, and judgment of physicians, pharmacists and other healthcare professionals involved with patient care at CLIENT facilities.