Prednisolone (Pred ForteĀ®)

About This Drug

Prednisolone is a steroid used to treat eye inflammation and other conditions. It is also used to prevent inflammation with certain chemotherapy. It is given in the eyes as drops.

Possible Side Effects

  • Eye discomfort, redness and/or irritation
  • Inflammation (swelling) of the eye
  • Dry and/or itchy eye
  • Blurred vision
  • Allergic reactions
  • Burning and/or stinging of the eye
  • Rash
  • Headache
  • Increased pressure of the eye and/or glaucoma, which can cause damage to the optic nerve, impair vision and cause clouding of the lens in your eye (cataracts)
  • Increased risk of viral, bacterial and fungal infection of the eye
  • Changes in the way food and drinks taste

Note: Not all possible side effects are included above.

Warnings and Precautions

  • Long-term use of this drug increases the risk of increased pressure and infection of the eye 
  • If you have a disease causing thinning of the cornea or sclera, you may be at an increased risk of developing small tears (perforation) of the eye
  • Prednisolone may cause slow wound healing of the eye
  • Prednisolone may cause symptoms of an eye infection to be less noticeable or worsened
  • Prednisolone contains sodium bisulfite, which can cause allergic type reactions, which can rarely be life threatening. Signs of allergic reaction to this drug may be swelling of the face, feeling like your tongue or throat are swelling, trouble breathing, rash, itching, fever, chills, feeling dizzy, and/or feeling that your heart is beating in a fast or not normal way. If this happens, do not take another dose of this drug. You should get urgent medical treatment.

Important Information

  • The preservative may be absorbed by soft contact lenses. It is recommended that you remove your lenses before applying the drops and wait at least 15 minutes before re-insertion.

Treating Side Effects

  • Taking good care of your mouth may help food taste better and improve your appetite.
  • Keeping your pain under control is important to your well-being. Please tell your doctor or nurse if you are experiencing pain.
  • If you get a rash do not put anything on it unless your doctor or nurse says you may. Keep the area around the rash clean and dry. Ask your doctor for medicine if your rash bothers you.

How to Take Your Medication

  • Shake well before using. Apply drops to your eye by pulling your lower eyelid down while bending your head backward. Follow your prescription for frequency. Do not touch tip of dropper as it may contaminate your medication. Do not allow the tip of the dropper to touch your eye as it may increase your risk of infection.
  • Missed dose: If you miss a dose, continue with your regular dosing schedule and contact your physician.
  • Handling: Wash your hands after handling your medicine, your caretakers should not handle your medicine with bare hands and should wear latex gloves.
  • Storage: Store this medicine upright at room temperature up to 25°C (77°F). Protect from freezing.

Food and Drug Interactions

  • There are no known interactions of prednisolone with food.
  • This drug may interact with other medicines. Tell your doctor and pharmacist about all the prescription and over-the-counter medicines and dietary supplements (vitamins, minerals, herbs and others) that you are taking at this time. Also, check with your doctor or pharmacist before starting any new prescription or over-the-counter medicines, or dietary supplements to make sure that there are no interactions.

When to Call the Doctor

Call your doctor or nurse if you have any of these symptoms and/or any new or unusual symptoms:

  • Fever of 100.4° F (38° C) or higher
  • Chills
  • Blurred vision or other changes in eyesight
  • Sensitivity to light
  • Pain or eye inflammation that lasts longer than 48 hours
  • If you think you may be pregnant
  • New rash and/or itching
  • Rash that is not relieved by prescribed medicines
  • Signs of allergic reaction: swelling of the face, feeling like your tongue or throat are swelling, trouble breathing, rash, itching, fever, chills, feeling dizzy, and/or feeling that your heart is beating in a fast or not normal way. If this happens, call 911 for emergency care.

Reproduction Warnings

  • Pregnancy warning: It is not known if this drug may harm an unborn child. For this reason, be sure to talk with your doctor if you are pregnant or planning to become pregnant while receiving this drug. Let your doctor know right away if you think you may be pregnant.
  • Breastfeeding warning: It is not known if this drug passes into breast milk. For this reason, women should talk to their doctor about the risks and benefits of breastfeeding during treatment with this drug because this drug may enter the breast milk and cause harm to a breastfeeding baby.
  • Fertility warning: Fertility studies have not been done with this drug. Talk with your doctor or nurse if you plan to have children.

Revised August 2019

This patient information was developed by Via Oncology, LLC © 2019. This information is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have.

CLIENT acknowledges that the Via Pathways and Via Portal are information management tools only, and that Via Oncology, LLC has not represented the Via Pathways or Via Portal as having the ability to diagnose disease, prescribe treatment, or perform any other tasks that constitute the practice of medicine. The clinical information contained in the Via Pathways and Via Portal are intended as a supplement to, and not a substitute for, the knowledge, expertise, skill, and judgment of physicians, pharmacists and other healthcare professionals involved with patient care at CLIENT facilities.